|
KMID : 0043319960190050406
|
|
Archives of Pharmacal Research
1996 Volume.19 No. 5 p.406 ~ p.410
|
|
|
Isolation of Handelin from Chrysanthemum boreale
|
|
Kang Sam-Sik
Kim Ju-Sun
Son Kun-Ho
Lee Chong-Ock
Kim Young-Hee
|
|
|
Abstract
|
|
|
|
The flowers of Chrysanthemum boreale afforded handelin, a unique guaianolide dimer and a mixture of n-hydrocarbons and n-hydrocarbon alcohols in addition to b-sitosterol and b-sitosterol glucoside. Detailed analysis of the - and -NMR spectra of handelin was carried out by the application of two-dimensional -COSY and - multiple-bond, multiple-quantum spectroscopic correlation techniques. Handelin was inactive in the in vitro anti-tumor activity.
|
|
|
KEYWORD
|
|
|
Chrysanthemum boreale, Compositare, Guaianolide dimer, Handelin, NMR as-signment, Anti-tumor activity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|